Vigil Neuroscience (NASDAQ:VIGL – Get Free Report) and Vericel (NASDAQ:VCEL – Get Free Report) are both medical companies, but which is the superior business? We will compare the two businesses based on the strength of their profitability, dividends, institutional ownership, analyst recommendations, valuation, earnings and risk.
Profitability
This table compares Vigil Neuroscience and Vericel’s net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Vigil Neuroscience | N/A | -76.02% | -62.85% |
| Vericel | 0.37% | 0.35% | 0.22% |
Volatility & Risk
Vigil Neuroscience has a beta of 1.95, indicating that its stock price is 95% more volatile than the S&P 500. Comparatively, Vericel has a beta of 1.67, indicating that its stock price is 67% more volatile than the S&P 500.
Analyst Ratings
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Vigil Neuroscience | 1 | 0 | 4 | 0 | 2.60 |
| Vericel | 0 | 0 | 7 | 0 | 3.00 |
Vigil Neuroscience currently has a consensus target price of $16.60, suggesting a potential upside of 334.55%. Vericel has a consensus target price of $57.71, suggesting a potential upside of 25.93%. Given Vigil Neuroscience’s higher probable upside, analysts plainly believe Vigil Neuroscience is more favorable than Vericel.
Insider and Institutional Ownership
83.6% of Vigil Neuroscience shares are owned by institutional investors. 33.0% of Vigil Neuroscience shares are owned by insiders. Comparatively, 5.2% of Vericel shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.
Valuation & Earnings
This table compares Vigil Neuroscience and Vericel”s gross revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Vigil Neuroscience | N/A | N/A | -$82.64 million | ($2.12) | -1.80 |
| Vericel | $214.52 million | 10.38 | -$3.18 million | ($0.01) | -4,583.00 |
Vericel has higher revenue and earnings than Vigil Neuroscience. Vericel is trading at a lower price-to-earnings ratio than Vigil Neuroscience, indicating that it is currently the more affordable of the two stocks.
Summary
Vericel beats Vigil Neuroscience on 8 of the 13 factors compared between the two stocks.
About Vigil Neuroscience
Vigil Neuroscience, Inc., a clinical-stage biotechnology company, focuses on developing treatments for rare and common neurodegenerative diseases by restoring the vigilance of microglia, the sentinel immune cells of the brain. Its lead candidate is VGL101(Iluzanebart), a human monoclonal antibody agonist targeting human triggering receptor expressed on myeloid cells 2 and is in a Phase 2 trial in patients with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), a rare and fatal neurodegenerative disease. The company is also developing VG-3927, an orally-available small molecule TREM2 agonist to treat common neurodegenerative diseases associated with microglial dysfunction, with an initial focus on Alzheimer’s disease in genetically defined subpopulations, which is being evaluated in a Phase 1 clinical trial. It has license agreement with Amgen Inc. to commercially develop, manufacture, use, distribute, and sell therapeutic products containing compounds that bind to TREM2. The company was incorporated in 2020 and is headquartered in Watertown, Massachusetts.
About Vericel
Vericel Corporation, a commercial-stage biopharmaceutical company, engages in the research, development, manufacture, and distribution of cellular therapies for sports medicine and severe burn care markets in North America. The company markets autologous cell therapy products comprising MACI, an autologous cultured chondrocytes on porcine collagen membrane for the repair of symptomatic, and single or multiple full-thickness cartilage defects of the knee; Epicel, a permanent skin replacement humanitarian use device for the treatment of adult and pediatric patients with deep-dermal or full-thickness burns; and NexoBrid, a biological orphan product for eschar removal in adults with deep partial-thickness and/or full-thickness thermal burns. The company was formerly known as Aastrom Biosciences, Inc. Vericel Corporation was incorporated in 1989 and is headquartered in Cambridge, Massachusetts.
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